Discrete mobility of single-stranded DNA in non-denaturing gel electrophoresis
نویسندگان
چکیده
منابع مشابه
Discrete mobility of single-stranded DNA in non-denaturing gel electrophoresis.
Gel electrophoresis is the standard method to separate, identify and purify nucleic acids. SSCP detects single base changes by altered mobility of single-stranded segments electrophoresed through non-denaturing polyacrylamide gels. Herein, changes in electrophoretic mobilities due to single base substitutions were measured for single-stranded segments of lengths ranging from 333 to 547 nt. A 48...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2000
ISSN: 1362-4962
DOI: 10.1093/nar/28.4.940